ARS-1323-alkyne |
| Catalog No.GC65480 |
L'ARS-1323-alcyne, un inhibiteur de la poche switch-II (S-IIP), est un rapporteur chimique conformationnel spécifique de l'état du nucléotide KRASG12C dans les cellules vivantes.
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Cas No.: 2436544-27-1
Sample solution is provided at 25 µL, 10mM.
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ARS-1323-alkyne, a switch-II pocket (S-IIP) inhibitor, is a conformational specific chemical reporter of KRASG12C nucleotide state in living cells[1].
[1]. Lou K,et al. KRASG12C inhibition produces a driver-limited state revealing collateral dependencies. Sci Signal. 2019 May 28;12(583). pii: eaaw9450.
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