ARS-1323-alkyne |
| カタログ番号GC65480 |
スイッチ II ポケット (S-IIP) 阻害剤である ARS-1323-アルキンは、生細胞における KRASG12C ヌクレオチド状態の構造特異的な化学レポーターです。
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Cas No.: 2436544-27-1
Sample solution is provided at 25 µL, 10mM.
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ARS-1323-alkyne, a switch-II pocket (S-IIP) inhibitor, is a conformational specific chemical reporter of KRASG12C nucleotide state in living cells[1].
[1]. Lou K,et al. KRASG12C inhibition produces a driver-limited state revealing collateral dependencies. Sci Signal. 2019 May 28;12(583). pii: eaaw9450.
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