ARS-1323-alkyne |
| Catalog No.GC65480 |
스위치-II 포켓(S-IIP) 억제제인 ARS-1323-알킨은 살아있는 세포에서 KRASG12C 뉴클레오타이드 상태의 구조적 특이적 화학적 리포터입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2436544-27-1
Sample solution is provided at 25 µL, 10mM.
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ARS-1323-alkyne, a switch-II pocket (S-IIP) inhibitor, is a conformational specific chemical reporter of KRASG12C nucleotide state in living cells[1].
[1]. Lou K,et al. KRASG12C inhibition produces a driver-limited state revealing collateral dependencies. Sci Signal. 2019 May 28;12(583). pii: eaaw9450.
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