AT-9010 tetrasodium |
| Catalog No.GC63412 |
AT-9010 tétrasodium, un métabolite actif de triphosphate d'AT-527, est un inhibiteur puissant de NiRAN (une fonction essentielle pour la réplication virale).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1621884-18-1
Sample solution is provided at 25 µL, 10mM.
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AT-9010 tetrasodium, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 tetrasodium can inhibit SARS-CoV-2 replication[1].
Substantial levels of the active triphosphate metabolite AT-9010 are formed in normal human bronchial and nasal epithelial cells incubated with 10 µM AT-511 (698 µM and 236 µM, respectively), with a half-life of at least 38 hours[1].
References:
[1]. Atea Pharmaceuticals Announces Publication of Preclinical Data Highlighting Potent Activity of AT-527 Against SARS-CoV-2. BOSTON, Feb. 08, 2021. Atea Pharmaceuticals, Inc.
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