AT-9010 tetrasodium |
| Katalog-Nr.GC63412 |
AT-9010 Tetranatrium, ein aktiver Metabolit von AT-527 Triphosphat, ist ein potenter Inhibitor von NiRAN (eine für die virale Replikation wesentliche Funktion).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1621884-18-1
Sample solution is provided at 25 µL, 10mM.
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AT-9010 tetrasodium, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 tetrasodium can inhibit SARS-CoV-2 replication[1].
Substantial levels of the active triphosphate metabolite AT-9010 are formed in normal human bronchial and nasal epithelial cells incubated with 10 µM AT-511 (698 µM and 236 µM, respectively), with a half-life of at least 38 hours[1].
References:
[1]. Atea Pharmaceuticals Announces Publication of Preclinical Data Highlighting Potent Activity of AT-527 Against SARS-CoV-2. BOSTON, Feb. 08, 2021. Atea Pharmaceuticals, Inc.
Average Rating: 5 (Based on Reviews and 24 reference(s) in Google Scholar.)
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