Nemifitide diTFA (Synonyms: INN 00835 diTFA) |
| Catalog No.GC39277 |
Le némifitide diTFA (INN 00835 diTFA) est un antidépresseur pentapeptide synthétique avec un potentiel d'action rapide.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 204992-09-6
Sample solution is provided at 25 µL, 10mM.
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Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action[1]. Nemifitide diTFA is a peptide analog of melanocyte-inhibiting factor (MIF)[2]. Nemifitide diTFA can cross the blood-brain barrier[3].
[1]. Kelly JP, et al. The effect of treatment with a new antidepressant, INN 00835, on platelet serotonin uptake in depressed patients. J Affect Disord. 1999 Oct;55(2-3):231-5. [2]. Overstreet DH, et al. Antidepressant-like effects of a novel pentapeptide, nemifitide, in an animal model of depression. Psychopharmacology (Berl). 2004 Sep;175(3):303-9. [3]. Montgomery SA, et al. Efficacy and safety of 30 mg/d and 45 mg/d nemifitide compared to placebo in major depressivedisorder. Int J Neuropsychopharmacol. 2006 Oct;9(5):517-28.
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