Disuccinimidyl Suberate (Synonyms: DSS, NSC 340008) |
| Catalog No.GC43480 |
Disuccinimidyl Suberate est un lien ADC non clivable utilisé dans la synthèse de conjugués anticorps-médicament (ADC).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 68528-80-3
Sample solution is provided at 25 µL, 10mM.
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Disuccinimidyl suberate (DSS) is a bifunctional cross-linking reagent which contains two N-hydroxysuccinimide esters that are reactive toward primary amines.[1][2]
Reference:
[1]. Hétu, P.O., Ouellet, M., Falgueyret, J.P., et al. Photo-crosslinking of proteins in intact cells reveals a dimeric structure of cyclooxygenase-2 and an inhibitor-sensitive oligomeric structure of microsomal prostaglandin E2 synthase-1. Archives of Biochemistry and Biophysics 477, 155-162 (2008).
[2]. Ding, H., and Johnson, G.V.W. New application of ß-galactosidase complementation to monitor tau self-association. Journal of Neurochemistry 106, 1545-1551 (2008).
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