(±)-Medicarpin |
| Catalog No.GC34962 |
(M) -Medicarpin, un pterocarpan, est un type d'isoflavonoïde isolé de plusieurs espèces de plantes médicinales ayant divers effets biologiques, notamment Sophora japonica, Zollernia paraensis et Platymiscium yucatamun, Machaerium aristulatum, Platymiscium floribundum, etc. (M) -Medicarpin inhibe puissamment l'ostéoclastogenèse et favorise la cicatrisation osseuse et augmente la masse osseuse par différenciation des ostéoblastes avec l'action ostéogénique médiée par le récepteur des œstrogènes (ER).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 33983-39-0
Sample solution is provided at 25 µL, 10mM.
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(±)-Medicarpin is a pterocarpan, a type of isoflavonoid. (±)-Medicarpin has been isolated from several medicinal plant species with various biological effects, including Sophora japonica as a phytoalexin, Zollernia paraensis and Platymiscium yucatamun with antifungal properties, Machaerium aristulatum, Platymiscium floribundum, and Brazilian red propolis with cytotoxic effects, and Dalbergia oliveri as a larvicidal compound. (±)-Medicarpin potently inhibits osteoclastogenesis and prevents estrogen-deficient bone loss but does not display uterine estrogenicity. It also promotes bone healing and increases bone mass by osteoblast differentiation with estrogen receptor (ER) β-mediated osteogenic action[1]. ERβ
[1]. Yang X, et al. Total Synthesis of (+)-Medicarpin. J Nat Prod. 2017 Dec 22;80(12):3284-3288.
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