(±)-Medicarpin |
| Katalog-Nr.GC34962 |
(±)-Medicarpin, ein Pterocarpan, ist eine Art Isoflavonoid, das aus mehreren Heilpflanzenarten mit verschiedenen biologischen Wirkungen isoliert wurde, darunter Sophora japonica, Zollernia paraensis und Platymiscium yucatamun, Machaerium aristulatum, Platymiscium floribundum und so weiter. (±)-Medicarpin hemmt wirksam die Osteoklastogenese und fördert die Knochenheilung und erhöht die Knochenmasse durch Osteoblastendifferenzierung mit Östrogenrezeptor (ER) β-vermittelter osteogener Wirkung.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 33983-39-0
Sample solution is provided at 25 µL, 10mM.
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(±)-Medicarpin is a pterocarpan, a type of isoflavonoid. (±)-Medicarpin has been isolated from several medicinal plant species with various biological effects, including Sophora japonica as a phytoalexin, Zollernia paraensis and Platymiscium yucatamun with antifungal properties, Machaerium aristulatum, Platymiscium floribundum, and Brazilian red propolis with cytotoxic effects, and Dalbergia oliveri as a larvicidal compound. (±)-Medicarpin potently inhibits osteoclastogenesis and prevents estrogen-deficient bone loss but does not display uterine estrogenicity. It also promotes bone healing and increases bone mass by osteoblast differentiation with estrogen receptor (ER) β-mediated osteogenic action[1]. ERβ
[1]. Yang X, et al. Total Synthesis of (+)-Medicarpin. J Nat Prod. 2017 Dec 22;80(12):3284-3288.
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