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Amotosalen hydrochloride (Synonyms: S-59)

Catalog No.GC35326

Le chlorhydrate d'amotosalen (S-59) est un composé de psoralène activé par la lumière, réticulant l'ADN et l'ARN, qui est utilisé pour neutraliser les agents pathogènes .

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Amotosalen hydrochloride Chemical Structure

Cas No.: 161262-45-9

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens[1].

When activated by light, Amotosalen binds to the nucleic acid of the pathogen and prevents replication. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells[1].

[1]. Amotosalen: Allogeneic Cellular Immunotherapies system, INTERCEPT Plasma System, INTERCEPT Platelet System, S 59. BioDrugs. 2003;17(1):66-8.

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Average Rating: 5 ★★★★★ (Based on Reviews and 23 reference(s) in Google Scholar.)

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