PHT-7.3 |
| Catalog No.GC36901 |
PHT-7.3 est un inhibiteur sélectif de l'amplificateur connecteur du suppresseur de kinase du domaine d'homologie de la pleckstrine (PH) Ras 1 (Cnk1) (Kd = 4,7 μM). PHT-7.3 inhibe mut-KRas, mais pas la croissance et la signalisation des cellules cancéreuses et tumorales des KRas de type sauvage. PHT-7.3 a une activité antitumorale.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1614225-93-2
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain, which inhibits mut-KRas, but not wild-type KRas cancer cell and tumor growth and signaling[1]. Cnk1 PH-domain[1]
[1]. Indarte M ,et al. An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors. Cancer Res. 2019 Jun 15;79(12):3100-3111.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *