GSK2018682 |
| Catalog No.GC31863 |
GSK2018682 est un agoniste des récepteurs S1P1 et S1P5 avec des pEC50 de 7,7 et 7,2, respectivement, et n'a aucune activité agoniste vis-À-vis de S1P2, S1P3 ou S1P4 humain.
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Cas No.: 1034688-30-6
Sample solution is provided at 25 µL, 10mM.
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GSK2018682 is an agonist for S1P1 and S1P5 receptor with pEC50s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4. GSK2018682 is used in the research of multiple sclerosis.
GSK2018682 is an agonist for S1P1 and S1P5 receptor with pEC50s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4[1].
[1]. Xu J, et al. Safety, pharmacokinetics, pharmacodynamics, and bioavailability of GSK2018682, a sphingosine-1-phosphate receptor modulator, in healthy volunteers. Clin Pharmacol Drug Dev. 2014 May;3(3):170-8.
Average Rating: 5 (Based on Reviews and 25 reference(s) in Google Scholar.)
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