L162389 |
Catalog No.GC30443 |
L162389 est un puissant antagoniste du récepteur AT1 de l'angiotensine avec un Ki de 28 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 169281-53-2
Sample solution is provided at 25 µL, 10mM.
L162389 is a potent antagonist of angiotensin AT1 receptor with Ki of 28 nM.
L-162,389 stimulates phosphatidylinositol turnover, albeit only to a small percentage of the angiotensin response. L-162,389 acts as angiotensin antagonist with IC50 value of 105 nM[1].
[1]. Perlman S, et al. Dual agonistic and antagonistic property of nonpeptide angiotensin AT1 ligands: susceptibility to receptor mutations. Mol Pharmacol. 1997 Feb;51(2):301-11.
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