L162389 |
| Catalog No.GC30443 |
L162389는 Ki가 28nM인 안지오텐신 AT1 수용체의 강력한 길항제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 169281-53-2
Sample solution is provided at 25 µL, 10mM.
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L162389 is a potent antagonist of angiotensin AT1 receptor with Ki of 28 nM.
L-162,389 stimulates phosphatidylinositol turnover, albeit only to a small percentage of the angiotensin response. L-162,389 acts as angiotensin antagonist with IC50 value of 105 nM[1].
[1]. Perlman S, et al. Dual agonistic and antagonistic property of nonpeptide angiotensin AT1 ligands: susceptibility to receptor mutations. Mol Pharmacol. 1997 Feb;51(2):301-11.
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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