L162389 |
| カタログ番号GC30443 |
L162389 は、28 nM の Ki を持つアンギオテンシン AT1 受容体の強力なアンタゴニストです。
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Cas No.: 169281-53-2
Sample solution is provided at 25 µL, 10mM.
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L162389 is a potent antagonist of angiotensin AT1 receptor with Ki of 28 nM.
L-162,389 stimulates phosphatidylinositol turnover, albeit only to a small percentage of the angiotensin response. L-162,389 acts as angiotensin antagonist with IC50 value of 105 nM[1].
[1]. Perlman S, et al. Dual agonistic and antagonistic property of nonpeptide angiotensin AT1 ligands: susceptibility to receptor mutations. Mol Pharmacol. 1997 Feb;51(2):301-11.
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