MAHMA NONOate (Synonyms: Methylamine hexamethylene methylamine NONOate) |
| Catalog No.GC19529 |
A NO donor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 146724-86-9
Sample solution is provided at 25 µL, 10mM.
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MAHMA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 1 minute and 3 minutes at 37°C and 22-25°C, respectively, (pH 7.4) to liberate 2 moles of NO per mole of parent compound.[1],[2]
Reference:
[1]. Hrabie, J.A., Klose, J.R., Wink, D.A., et al. New nitric oxide-releasing zwitterions derived from polyamines The Journal of Organic Chemistry 58, 1472-1476 (1993).
[2]. Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms Methods in Enzymology 268, 281-293 (1996).
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