MeOSuc-AAPV-pNA |
| Catalog No.GC44156 |
MeOSuc-AAPV-pNA est un substrat fluorogène sensible des leucocytes humains et de l'élastase pancréatique porcine.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 70967-90-7
Sample solution is provided at 25 µL, 10mM.
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Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm.
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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