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MS7972

Catalog No.GC62322

MS7972 est une petite molécule qui bloque l'association de la protéine de liaison p53 humaine et CREB. MS7972 peut presque complètement bloquer cette interaction BRD À 50 μM.

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MS7972 Chemical Structure

Cas No.: 352553-42-5

Taille Prix Stock Qté
5 mg
207,00 $US
En stock
10 mg
351,00 $US
En stock
25 mg
666,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

MS7972 is a small molecule that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM[1].

Addition of MS7972 to the CBP BRD results in emission at 445 nm and quenching of the CBP BRD due to resonance energy transfer[1].

[1]. Sachchidanand, et al. Target structure-based discovery of small molecules that block human p53 and CREB binding protein association. Chem Biol. 2006 Jan;13(1):81-90.

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Average Rating: 5 ★★★★★ (Based on Reviews and 35 reference(s) in Google Scholar.)

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