N106 |
| Catalog No.GC50234 |
N106 est un activateur de SUMOylation de l'ATPase calcique du réticulum sarcoplasmique (SERCA2a) de première classe.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 862974-25-2
Sample solution is provided at 25 µL, 10mM.
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Activator of SUMO-activating enzyme, E1 ligase. Increases SERCA2a SUMOylation and activity, and enhances contractility in rat cardiomyocytes in vitro. Improves ventricular function in a mouse model of heart disease.
Kho et al (2015) Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure. Nat.Commun. 6 7229 PMID:26068603
Average Rating: 5 (Based on Reviews and 10 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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