>>Signaling Pathways>> Ubiquitination/ Proteasome>> E3 Ligase>>N106

N106

Catalog No.GC50234

N106은 동급 최초의 근형질 세망 칼슘 ATPase(SERCA2a) SUMOylation 활성화제입니다.

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N106 Chemical Structure

Cas No.: 862974-25-2

Size 가격 재고 수량
10 mg
US$212.00
재고 있음
50 mg
US$790.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Activator of SUMO-activating enzyme, E1 ligase. Increases SERCA2a SUMOylation and activity, and enhances contractility in rat cardiomyocytes in vitro. Improves ventricular function in a mouse model of heart disease.

Kho et al (2015) Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure. Nat.Commun. 6 7229 PMID:26068603

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 10 reference(s) in Google Scholar.)

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