N106 |
| カタログ番号GC50234 |
N106 は、クラス最高の筋小胞体カルシウム ATPase (SERCA2a) SUMO 化活性化因子です。
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Cas No.: 862974-25-2
Sample solution is provided at 25 µL, 10mM.
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Activator of SUMO-activating enzyme, E1 ligase. Increases SERCA2a SUMOylation and activity, and enhances contractility in rat cardiomyocytes in vitro. Improves ventricular function in a mouse model of heart disease.
Kho et al (2015) Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure. Nat.Commun. 6 7229 PMID:26068603
Average Rating: 5 (Based on Reviews and 10 reference(s) in Google Scholar.)
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