Nav1.7-IN-2 |
| Catalog No.GC31002 |
Nav1.7-IN-2 est un inhibiteur des canaux sodiques voltage-dépendants (Nav), en particulier Nav 1.7, avec IC50 de 80 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1332295-35-8
Sample solution is provided at 25 µL, 10mM.
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Nav1.7-IN-2 is an inhibitor of voltage-gated sodium channels (Nav), in particular Nav 1.7, with IC50 of 80 nM.IC50 value: 80 nMTarget: Nav 1.7Nav1.7-IN-2 is useful for the treatment of diseases treatable by inhibition of these channels, in particular, chronic pain disorder. The more detailed information please refer to WO 2011103196 A1. Nav1.7-IN-2 is a Nav1.7 channel inhibitor extracted from patent WO/2011103196 A1, compound example J, has an IC50 of 80 nM.
[1]. Bregman Howard, et al. Preparation of aryl carboxamide derivatives as sodium channel inhibitors for treatment of pain. From PCT Int. Appl. (2011), WO 2011103196 A1 20110825.
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