>>Signaling Pathways>> Membrane Transporter/Ion Channel>> Sodium Channel>>Nav1.7-IN-2

Nav1.7-IN-2

Catalog No.GC31002

Nav1.7-IN-2는 IC50이 80nM인 전압 개폐 나트륨 채널(Nav), 특히 Nav 1.7의 억제제입니다.

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Nav1.7-IN-2 Chemical Structure

Cas No.: 1332295-35-8

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$354.00
재고 있음
5mg
US$321.00
재고 있음
10mg
US$459.00
재고 있음
50mg
US$1,379.00
재고 있음
100mg
US$1,930.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Nav1.7-IN-2 is an inhibitor of voltage-gated sodium channels (Nav), in particular Nav 1.7, with IC50 of 80 nM.IC50 value: 80 nMTarget: Nav 1.7Nav1.7-IN-2 is useful for the treatment of diseases treatable by inhibition of these channels, in particular, chronic pain disorder. The more detailed information please refer to WO 2011103196 A1. Nav1.7-IN-2 is a Nav1.7 channel inhibitor extracted from patent WO/2011103196 A1, compound example J, has an IC50 of 80 nM.

[1]. Bregman Howard, et al. Preparation of aryl carboxamide derivatives as sodium channel inhibitors for treatment of pain. From PCT Int. Appl. (2011), WO 2011103196 A1 20110825.

리뷰

Review for Nav1.7-IN-2

Average Rating: 5 ★★★★★ (Based on Reviews and 33 reference(s) in Google Scholar.)

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