NITD-2 |
| Catalog No.GC64559 |
NITD-2, un inhibiteur de la polymérase du virus de la dengue (DENV), inhibe l'élongation de l'ARN médiée par le RdRp du DENV.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1197896-79-9
Sample solution is provided at 25 µL, 10mM.
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NITD-2, a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly[1].
NITD-2 inhibits de novo RNA synthesis[1].NITD-2 exhibited no antiviral activity in cell culture resulted from the poor cell penetratration[1].
[1]. Pornwaratt Niyomrattanakit, et al. Inhibition of dengue virus polymerase by blocking of the RNA tunnel. J Virol. 2010 Jun;84(11):5678-86.
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