NITD-2 |
| Catalog No.GC64559 |
뎅기 바이러스(DENV) 중합효소 억제제인 NITD-2는 DENV RdRp 매개 RNA 신장을 억제합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1197896-79-9
Sample solution is provided at 25 µL, 10mM.
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NITD-2, a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly[1].
NITD-2 inhibits de novo RNA synthesis[1].NITD-2 exhibited no antiviral activity in cell culture resulted from the poor cell penetratration[1].
[1]. Pornwaratt Niyomrattanakit, et al. Inhibition of dengue virus polymerase by blocking of the RNA tunnel. J Virol. 2010 Jun;84(11):5678-86.
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