Propofol |
Catalog No.GC39424 |
Le propofol active puissamment et directement le récepteur GABAA et inhibe la transmission synaptique excitatrice médiée par le récepteur du glutamate.
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Cas No.: 2078-54-8
Sample solution is provided at 25 µL, 10mM.
Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties and is used for sedation and hypnotic[1].
[1]. R Nadeson, et al. Antinociceptive Properties of Propofol: Involvement of Spinal Cord Gamma-Aminobutyric acid(A) Receptors. J Pharmacol Exp Ther . 1997 Sep;282(3):1181-6.
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