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Accueil >> Signaling Pathways >> Cardiovascular >> Cholesterol Metabolism

Cholesterol Metabolism

Products for  Cholesterol Metabolism

  1. Cat.No. Nom du produit Informations
  2. GC49690 (3R,5R)-Rosuvastatin (calcium salt) A potential impurity found in bulk preparations of rosuvastatin (3R,5R)-Rosuvastatin (calcium salt) Chemical Structure
  3. GC40452 15(S)-HETE MaxSpec® Standard 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE MaxSpec® Standard Chemical Structure
  4. GC40457 19(R)-HETE

    19(R)-Hydroxyeicosatetraenoic Acid

     19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. 19(R)-HETE Chemical Structure
  5. GC40417 19-hydroxy Cholesterol 19-hydroxy Cholesterol is formed during metabolic oxidation of cholesterol. 19-hydroxy Cholesterol Chemical Structure
  6. GC49671 2,3-Oxidosqualene

    (3R,S)-Oxidosqualene, Squalene 2,3-oxide

     An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene Chemical Structure
  7. GC41614 24-dehydro Cholesterol

    Desmosterol

    Le 24-déhydrocholestérol est une molécule similaire au cholestérol.

     24-dehydro Cholesterol Chemical Structure
  8. GC46243 24-dehydro Cholesterol-d6

    Desmosterol-d6

     An internal standard for the quantification of 24-dehydro cholesterol 24-dehydro Cholesterol-d6 Chemical Structure
  9. GC46528 25-hydroxy Cholesterol-d6 An internal standard for the quantification of 25hydroxy cholesterol 25-hydroxy Cholesterol-d6 Chemical Structure
  10. GC48449 28-(Poc-amino)betulin 28-(Poc-amino)betulin Chemical Structure
  11. GC62033 3α-Hydroxy pravastatin sodium

    3α-Isopravastatin, R-416

     3α ; - L'hydroxypravastatine sodique est le principal métabolite de la pravastatine. 3α-Hydroxy pravastatin sodium Chemical Structure
  12. GC40799 3-hydroxy-3-Methylglutaric anhydride

    Dicrotalic anhydride, HMG anhydride

     The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase mediates the rate-limiting step in cholesterol synthesis, converting HMG-CoA to mevalonate. 3-hydroxy-3-Methylglutaric anhydride Chemical Structure
  13. GC42405 4-hydroxy Atorvastatin (calcium salt)

    p-hydroxy Atorvastatin, para-hydroxy Atorvastatin

     4-hydroxy Atorvastatin is a metabolite of atorvastatin, an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias. 4-hydroxy Atorvastatin (calcium salt) Chemical Structure
  14. GC18425 4-hydroxy Atorvastatin lactone

    p-hydroxy Atorvastatin lactone, para-hydroxy Atorvastatin lactone

    4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.

     4-hydroxy Atorvastatin lactone Chemical Structure
  15. GC40535 6,15-diketo-13,14-dihydro Prostaglandin F1α

    6,15diketo13,14dihydro PGF1α

     6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2. 6,15-diketo-13,14-dihydro Prostaglandin F1α Chemical Structure
  16. GC46889 Atorvastatin (calcium salt hydrate) An HMG-CoA reductase inhibitor Atorvastatin (calcium salt hydrate) Chemical Structure
  17. GC49421 Atorvastatin lactone-d5 An internal standard for the quantification of atorvastatin lactone Atorvastatin lactone-d5 Chemical Structure
  18. GC46890 Atorvastatin-d5 (calcium salt) An internal standard for the quantification of atorvastatin Atorvastatin-d5 (calcium salt) Chemical Structure
  19. GC46911 Beauveriolide I Le beauvériolide I est le métabolite des champignons entomopathogènes Beauveria sp. Beauveriolide I Chemical Structure
  20. GC46912 Beauveriolide III Le beauvériolide III est un inhibiteur de la formation de gouttelettes lipidiques dans les macrophages de souris. Beauveriolide III Chemical Structure
  21. GC45390 Benazepril Acyl-β-D-Glucuronide

    Benazapril Glucuronide

       Benazepril Acyl-β-D-Glucuronide Chemical Structure
  22. GC19530 Brassicasterol Le brassicastérol, un métabolite de l'ergostérol, joue un rÔle dans l'effet inhibiteur sur la promotion de la carcinogenèse vésicale via la signalisation androgénique . Brassicasterol Chemical Structure
  23. GC43160 CAY10485

    3,4dihydroxy Hydrocinnamic acid (LAspartic acid dibenzyl ester) amide

     Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10485 Chemical Structure
  24. GC40869 CAY10486

    4Hydroxycinnamic acid (Lphenylalanine methyl ester) amide

     Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 Chemical Structure
  25. GC47085 Cholesterol-d7

    Provitamin D-d7

     An internal standard for the quantification of cholesterol Cholesterol-d7 Chemical Structure
  26. GC90700 Dendrogenin A

    Un modulateur sélectif de LXR et un inhibiteur de ChEH.

     Dendrogenin A Chemical Structure
  27. GC47367 Fluvastatin (sodium salt hydrate) An HMG-CoA reductase inhibitor Fluvastatin (sodium salt hydrate) Chemical Structure
  28. GC49303 Ganoderic Acid DM L'acide ganodérique DM, un triterpénoÏde naturel isolé de Ganoderma lucidum, induit des dommages À l'ADN, l'arrêt du cycle cellulaire G1 et l'apoptose dans les cellules cancéreuses du sein humain. Ganoderic Acid DM Chemical Structure
  29. GC43745 Geranyl Pyrophosphate (triammonium salt)

    GDP, Geranyl Diphosphate, GPP

    Le pyrophosphate de géranyle (sel de triammonium) est un intermédiaire clé dans la voie de biosynthèse des isoprénoïdes (IBP).

     Geranyl Pyrophosphate (triammonium salt) Chemical Structure
  30. GC45801 Hesperetin-13C-d3 A neuropeptide with diverse biological activities Hesperetin-13C-d3 Chemical Structure
  31. GC43883 Hymeglusin

    Antibiotic 1233A

     L'hyméglusine, en tant qu'antibiotique fongique β-lactone, est un inhibiteur de la HMG-CoA synthase (IC50 = 0,12 μM). Hymeglusin Chemical Structure
  32. GC49486 Meglutol-d3

    Dicrotalic Acid-d3, 3-hydroxy 3-methyl Glutaric Acid-d3, HMG-d3, 3-methyl-3-Hydroxyglutaric Acid-d3, Medroglutaric Acid-d3, 3-hydroxy-3-Methylglutaric Acid-d3

     An internal standard for the quantification of meglutol Meglutol-d3 Chemical Structure
  33. GC48418 N-(2-Poc-ethyl)betulin amide N-(2-Poc-ethyl)betulin amide Chemical Structure
  34. GC47756 N-desmethyl Rosuvastatin (sodium salt hydrate) An active metabolite of rosuvastatin N-desmethyl Rosuvastatin (sodium salt hydrate) Chemical Structure
  35. GC44497 Oleic Acid-2,6-diisopropylanilide AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleic Acid-2,6-diisopropylanilide Chemical Structure
  36. GC44590 Pellitorine La pellitorine est un composé isolé des racines de Piper nigrum. La pellitorine présente de fortes activités cytotoxiques contre les lignées cellulaires HL60 et MCT-7. Pellitorine a le potentiel pour la recherche de maladies cancéreuses. Pellitorine Chemical Structure
  37. GC49340 Pitavastatin lactone-d4 An internal standard for the quantification of pitavastatin lactone Pitavastatin lactone-d4 Chemical Structure
  38. GC40220 Pravastatin-d3 (sodium salt) Le sel de sodium de pravastatine-d3 (CS-514-d3) est le sel de sodium de pravastatine marqué au deutérium. Pravastatin-d3 (sodium salt) Chemical Structure
  39. GC49107 Rosuvastatin lactone

    (+)-Rosuvastatin lactone, Rosuvastatin-5S-lactone, RSTL

     The lactone form of rosuvastatin Rosuvastatin lactone Chemical Structure
  40. GC48060 Rosuvastatin-d6 (sodium salt) An internal standard for the quantification of rosuvastatin Rosuvastatin-d6 (sodium salt) Chemical Structure
  41. GC49333 SH-42

    Un inhibiteur de DHCR24

     SH-42 Chemical Structure
  42. GC50196 Simvastatin - d6

    SVA-d6

     Deuterated simvastatin Simvastatin - d6 Chemical Structure
  43. GC45017 Terpendole C Le terpendole C, produit par Albophoma yamanashiensis, présente une puissante activité inhibitrice contre l'acyl-CoA : cholestérol acyltransférase (ACAT). Terpendole C Chemical Structure
  44. GC45060 TMP-153 Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and cholesterol accumulation in vascular tissues. TMP-153 Chemical Structure
  45. GC45090 Triparanol

    MER-29, NSC 65345

     Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 μM), which is an enzyme involved in the biosynthesis of cholesterol. Triparanol Chemical Structure

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