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Accueil >> Signaling Pathways >> Cardiovascular >> Cholesterol Metabolism

Cholesterol Metabolism

Products for  Cholesterol Metabolism

  1. Cat.No. Nom du produit Informations
  2. GC49690 (3R,5R)-Rosuvastatin (calcium salt) A potential impurity found in bulk preparations of rosuvastatin (3R,5R)-Rosuvastatin (calcium salt) Chemical Structure
  3. GC40457 19(R)-HETE 19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. 19(R)-HETE Chemical Structure
  4. GC40417 19-hydroxy Cholesterol 19-hydroxy Cholesterol is formed during metabolic oxidation of cholesterol. 19-hydroxy Cholesterol Chemical Structure
  5. GC49671 2,3-Oxidosqualene An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene Chemical Structure
  6. GC41614 24-dehydro Cholesterol

    Le 24-déhydrocholestérol est une molécule similaire au cholestérol.

     24-dehydro Cholesterol Chemical Structure
  7. GC46243 24-dehydro Cholesterol-d6 An internal standard for the quantification of 24-dehydro cholesterol 24-dehydro Cholesterol-d6 Chemical Structure
  8. GC46528 25-hydroxy Cholesterol-d6 An internal standard for the quantification of 25hydroxy cholesterol 25-hydroxy Cholesterol-d6 Chemical Structure
  9. GC40799 3-hydroxy-3-Methylglutaric anhydride The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase mediates the rate-limiting step in cholesterol synthesis, converting HMG-CoA to mevalonate. 3-hydroxy-3-Methylglutaric anhydride Chemical Structure
  10. GC42405 4-hydroxy Atorvastatin (calcium salt) 4-hydroxy Atorvastatin is a metabolite of atorvastatin, an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias. 4-hydroxy Atorvastatin (calcium salt) Chemical Structure
  11. GC18425 4-hydroxy Atorvastatin lactone

    4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.

     4-hydroxy Atorvastatin lactone Chemical Structure
  12. GC40535 6,15-diketo-13,14-dihydro Prostaglandin F1α 6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2. 6,15-diketo-13,14-dihydro Prostaglandin F1α Chemical Structure
  13. GC46889 Atorvastatin (calcium salt hydrate) An HMG-CoA reductase inhibitor Atorvastatin (calcium salt hydrate) Chemical Structure
  14. GC49421 Atorvastatin lactone-d5 An internal standard for the quantification of atorvastatin lactone Atorvastatin lactone-d5 Chemical Structure
  15. GC46890 Atorvastatin-d5 (calcium salt) An internal standard for the quantification of atorvastatin Atorvastatin-d5 (calcium salt) Chemical Structure
  16. GC46911 Beauveriolide I Le beauvériolide I est le métabolite des champignons entomopathogènes Beauveria sp. Beauveriolide I Chemical Structure
  17. GC46912 Beauveriolide III Le beauvériolide III est un inhibiteur de la formation de gouttelettes lipidiques dans les macrophages de souris. Beauveriolide III Chemical Structure
  18. GC19530 Brassicasterol Le brassicastérol, un métabolite de l'ergostérol, joue un rÔle dans l'effet inhibiteur sur la promotion de la carcinogenèse vésicale via la signalisation androgénique . Brassicasterol Chemical Structure
  19. GC43160 CAY10485 Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10485 Chemical Structure
  20. GC40869 CAY10486 Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 Chemical Structure
  21. GC47085 Cholesterol-d7 An internal standard for the quantification of cholesterol Cholesterol-d7 Chemical Structure
  22. GC47367 Fluvastatin (sodium salt hydrate) An HMG-CoA reductase inhibitor Fluvastatin (sodium salt hydrate) Chemical Structure
  23. GC49303 Ganoderic Acid DM L'acide ganodérique DM, un triterpénoÏde naturel isolé de Ganoderma lucidum, induit des dommages À l'ADN, l'arrêt du cycle cellulaire G1 et l'apoptose dans les cellules cancéreuses du sein humain. Ganoderic Acid DM Chemical Structure
  24. GC43745 Geranyl Pyrophosphate (triammonium salt)

    Le pyrophosphate de géranyle (sel de triammonium) est un intermédiaire clé dans la voie de biosynthèse des isoprénoïdes (IBP).

     Geranyl Pyrophosphate (triammonium salt) Chemical Structure
  25. GC43883 Hymeglusin L'hyméglusine, en tant qu'antibiotique fongique β-lactone, est un inhibiteur de la HMG-CoA synthase (IC50 = 0,12 μM). Hymeglusin Chemical Structure
  26. GC49486 Meglutol-d3 An internal standard for the quantification of meglutol Meglutol-d3 Chemical Structure
  27. GC47756 N-desmethyl Rosuvastatin (sodium salt hydrate) An active metabolite of rosuvastatin N-desmethyl Rosuvastatin (sodium salt hydrate) Chemical Structure
  28. GC44497 Oleic Acid-2,6-diisopropylanilide AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleic Acid-2,6-diisopropylanilide Chemical Structure
  29. GC44590 Pellitorine La pellitorine est un composé isolé des racines de Piper nigrum. La pellitorine présente de fortes activités cytotoxiques contre les lignées cellulaires HL60 et MCT-7. Pellitorine a le potentiel pour la recherche de maladies cancéreuses. Pellitorine Chemical Structure
  30. GC49340 Pitavastatin lactone-d4 An internal standard for the quantification of pitavastatin lactone Pitavastatin lactone-d4 Chemical Structure
  31. GC40220 Pravastatin-d3 (sodium salt) Le sel de sodium de pravastatine-d3 (CS-514-d3) est le sel de sodium de pravastatine marqué au deutérium. Pravastatin-d3 (sodium salt) Chemical Structure
  32. GC49107 Rosuvastatin lactone The lactone form of rosuvastatin Rosuvastatin lactone Chemical Structure
  33. GC48060 Rosuvastatin-d6 (sodium salt) An internal standard for the quantification of rosuvastatin Rosuvastatin-d6 (sodium salt) Chemical Structure
  34. GC49333 SH-42

    Un inhibiteur de DHCR24

     SH-42 Chemical Structure
  35. GC50196 Simvastatin - d6 Deuterated simvastatin Simvastatin - d6 Chemical Structure
  36. GC45017 Terpendole C Le terpendole C, produit par Albophoma yamanashiensis, présente une puissante activité inhibitrice contre l'acyl-CoA : cholestérol acyltransférase (ACAT). Terpendole C Chemical Structure
  37. GC45060 TMP-153 Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and cholesterol accumulation in vascular tissues. TMP-153 Chemical Structure
  38. GC45090 Triparanol Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 μM), which is an enzyme involved in the biosynthesis of cholesterol. Triparanol Chemical Structure

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