2'-O,4'-C-Methylenecytidine (Synonyms: LNA-C(Bz)) |
| カタログ番号GC66654 |
2'-O,4'-C-メチレンシチジン (LNA-C(Bz)) は、固定された N 型コンフォメーションを持つ二環式ヌクレオシド類似体です。 2'-O,4'-C-メチレンシチジンは、オリゴヌクレオチドの合成に使用できます。 2'-O,4'-C-メチレンシチジンは、相補的な DNA 鎖および RNA 鎖と二重鎖を形成します。
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Cas No.: 206055-69-8
Sample solution is provided at 25 µL, 10mM.
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2'-O,4'-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2'-O,4'-C-Methylenecytidine can be used to synthesize oligonucleotides. 2'-O,4'-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands[1][2].
[1]. bicyclic nucleoside analogue, N-type conformation, synthesize oligonucleotides, duplexes
[2]. Obika S, et, al. Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides. Tetrahedron Letters. 1998 Jul 23; 39(30):5401-04.
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