5,7,8-Trimethoxyflavone |
| カタログ番号GC60526 |
Andrographis echioides から分離された 5,7,8-トリメトキシフラボン (ノルウォゴニン 5,7,8-トリメチル エーテル) は、39.1 μM の IC50 で NO を阻害します。
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Cas No.: 23050-38-6
Sample solution is provided at 25 µL, 10mM.
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5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity[1].
5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether; 8, 16, 32, 64 μM; for 24 hours) decreases NO production in a dose-dependent manner in RAW 264.7 macrophages. 5,7,8-Trimethoxyflavone does not change lipopolysaccharide (LPS)-induced (100 ng/mL) cell viability[1].
[1]. De-Yang Shen, et al. Chemical constituents from Andrographis echioides and their anti-inflammatory activity. Int J Mol Sci. 2012 Dec 27;14(1):496-514.
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