ADT-OH (Synonyms: ACS1) |
| カタログ番号GC42742 |
ADT-OH は、硫化水素放出ドナーです。 ADT-OH はアポトーシスを誘導し、FADD をアップレギュレートすることにより、in vivo でメラノーマの発生を抑制します。 ADT-OH は、がん疾患の研究の可能性を秘めています。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 18274-81-2
Sample solution is provided at 25 µL, 10mM.
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ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. It can be readily esterified with other moieties. For example, it can be coupled with therapeutics like nonsteroidal anti-inflammatory drugs, as in the generation of ATB-343 . ADT-OH has also been linked with a mitochondria-targeting motif to produce AP-39 , which selectively increases mitochondrial H2S levels. ADT-OH is used both in cells and in animals for comparative studies with derived chimeras.
Average Rating: 5 (Based on Reviews and 20 reference(s) in Google Scholar.)
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