Alemtuzumab (Synonyms: Campath-IH; Lemtrada; MabCampath) |
| カタログ番号GC66199 |
Alemtuzumab (Campath-IH) は、CD52 に対するヒト化モノクローナル抗体です。CD52 は、ほとんどのリンパ系細胞の表面に発現する糖タンパク質であり、程度は低いものの骨髄系細胞タイプにも発現します。 Alemtuzumab は、CD52 抗原を選択的に標的としてリンパ球の大幅な枯渇を誘導し、続いて調節表現型を有する T 細胞および B 細胞を回復させます。
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Cas No.: 216503-57-0
Sample solution is provided at 25 µL, 10mM.
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Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52, a glycoprotein expressed on the surface of most lymphoid, and to a lesser extent, myeloid cell types. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes[1][2].
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