Aspoxicillin |
| カタログ番号GC63886 |
アスポキシシリンは、MIC90 値が <= 0.05 μg/ml の Actinobacillus pleuropneumoniae の 68 分離株に対する広域スペクトルの抗菌剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 63358-49-6
Sample solution is provided at 25 µL, 10mM.
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Aspoxicillin is a broad-spectrum antimicrobial agent against 68 isolates of Actinobacillus pleuropneumoniae with an MIC90 value of <= 0.05 μg/ml. Aspoxicillin has a long half-life in mouse serum of 55 minutes[1][2].
Aspoxicillin is a semisynthetic penicillin derivative[2]Aspoxicillin induces postantibiotic effects (PAEs) against Staphylococcus aureus Smith of 1.7 h in vitro[2].
Aspoxicillin induces PAEs against Staphylococcus aureus Smith of 5.2 h in vivo in a thigh infection model in neutropenic mice[2].
[1]. Yoshimura H, et al. Comparative in vitro activity of 16 antimicrobial agents against Actinobacillus pleuropneumoniae. Vet Res Commun. 2002 Jan;26(1):11-9.
[2]. Oshida T, et al. Activity of sub-minimal inhibitory concentrations of aspoxicillin in prolonging the postantibiotic effect against Staphylococcus aureus. J Antimicrob Chemother. 1990 Jul;26(1):29-38.
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