Betamethasone 17-benzoate |
カタログ番号GC33890
One-Click Copy Product Info
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ベタメタゾン 17-安息香酸エステルは代表的なステロイドであり、再発性の無光性潰瘍 (RAU) の治療に使用できます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 22298-29-9
Sample solution is provided at 25 µL, 10mM.
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Betamethasone 17-benzoate is a representative steroid, which can be used in the treatment of recurrent aphothous ulcers (RAU).
Betamethasone 17-benzoate is the topical steroid[1]. Betamethasone 17-benzoate is a local corticosteroid[2]. A double-blind study of the effectiveness of Betamethasone 17-benzoate in the treatment of recurrent aphothous ulcers (RAU) is concucted. Betamethasone 17-benzoate is found to be effective in reducing symptoms and shortening healing time but not in preventing recurrences[3].
[1]. Barry BW, et al. Optimization of bioavailability of topical steroids: penetration enhancers under occlusion. J Invest Dermatol. 1984 Jan;82(1):49-52. [2]. ZFA (Stuttgart). 1978 Jul 10;54(19):1031-2. [3]. Merchant HW, et al. Betamethasone-17-benzoate in the treatment of recurrent aphthous ulcers. Oral Surg Oral Med Oral Pathol. 1978 Jun;45(6):870-5.
| Cas No. | 22298-29-9 | SDF | |
| Canonical SMILES | O=C(C1=CC=CC=C1)O[C@]2([C@@]3([C@@]([C@@]4([H])[C@@](F)([C@@]5(C(CC4)=CC(C=C5)=O)C)[C@@H](O)C3)([H])C[C@@H]2C)C)C(CO)=O | ||
| Formula | C29H33FO6 | M.Wt | 496.57 |
| 溶解度 | Soluble in DMSO | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 2.0138 mL | 10.0691 mL | 20.1381 mL |
| 5 mM | 402.8 μL | 2.0138 mL | 4.0276 mL |
| 10 mM | 201.4 μL | 1.0069 mL | 2.0138 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)