BigLEN (rat) |
| カタログ番号GC50415 |
BigLEN (ラット) は、1.6 nM の EC50 を持つ強力な GPR171 アゴニストです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 369377-66-2
Sample solution is provided at 25 µL, 10mM.
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Potent GPR171 agonist (EC50 = 1.6 nM). ProSAAS-derived peptide. Regulates body weight in mice and promotes the outgrowth of neurites in Neuro2A cells.
Gomes et al (2013) GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proc.Natl.Acad.Sci.USA. 110 16211 PMID:24043826 |Mack et al (2019) Neuropeptide PEN and its receptor GPR83: distribution, signaling, and regulation. ACS Chem.Neurosci. 10 1884 PMID:30726666
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
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