bio-THZ1 |
| カタログ番号GC62653 |
bio-THZ1 は、THZ1 のビオチン化バージョンであり、CDK7 に不可逆的に結合します。 THZ1 は、IC50 が 3.2 nM の選択的かつ強力な共有結合 CDK7 阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1604811-14-4
Sample solution is provided at 25 µL, 10mM.
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bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM[1].
[1]. Kwiatkowski N, et al. Targeting transcription regulation in cancer with a covalent CDK7 inhibitor. Nature. 2014 Jul 31;511(7511):616-20.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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