Burnettramic Acid A |
| カタログ番号GC48376 |
多様な生物学的活性を持つ真菌代謝産物
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2334483-46-2
Sample solution is provided at 25 µL, 10mM.
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Burnettramic acid A is a fungal metabolite originally isolated from A. burnettii that has diverse biological activities.1 It is active against B. subtilis, S. aureus, C. albicans, and S. cerevisiae (IC50s = 2.3, 5.9, 0.5, and 0.2 µg/ml, respectively). Burnettramic acid A is cytotoxic to NS-1 murine myeloma cells but not neonatal foreskin fibroblasts (IC50s = 13.8 and >100 µg/ml, respectively).
1.Li, H., Gilchrist, C.L.M., Lacey, H.J., et al.Discovery and heterologous biosynthesis of the burnettramic acids: Rare PKS-NRPS-derived bolaamphiphilic pyrrolizidinediones from an Australian fungus, Aspergillus burnettiiOrg. Lett.21(5)1287-1291(2019)
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