(D-Arg¹,D-Trp⁵·⁷·⁹,Leu¹¹)-Substance P |
カタログ番号GA20074 |
このSubstance Pアナログは、in vitroで小細胞肺癌(SCLC)細胞の成長を非常に強力に広範囲に抑制するネウロペプチド阻害剤です(IC?? = 5 µM)。さらに、in vitroでシグナル伝達経路を強力に阻害し、in vivoでSCLCキセノグラフトの成長を有意に遅延させました。したがって、これはSCLC治療上有用なものとなる可能性があります。
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Cas No.: 122481-75-8
Sample solution is provided at 25 µL, 10mM.
This substance P analog is a very potent broad-spectrum neuropeptide inhibitor for small cell lung cancer (SCLC) cell growth in vitro (IC50 = 5 µM). Moreover it potently inhibited signal transduction pathways in vitro and significantly delayed the
Average Rating: 5
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