(Thr(PO₃H₂)²³¹)-Tau Peptide (225-237) |
カタログ番号GA20307 |
アルツハイマー病の初期段階でpThr²³¹-Pro²³²モチーフのトランス-シス変換が観察されました。Pin1は異性化を逆転することによって、その結果生じる病原性tauの蓄積を防止します。
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Cas No.: 1670270-09-3
Sample solution is provided at 25 µL, 10mM.
A trans-cis conversion of the pThr²³¹-Pro²³² motif has been observed during early stages of Alzheimer's disease. Pin1 prevents the accumulation of the resulting pathogenic form of tau by reverting the isomerization.
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