Carbamoyl-Asp-OH . magnesium salt/Carbamoyl-Asp-OH . dipotassium salt (1:1) |
| カタログ番号GA21245 |
E.coliジヒドロオロターゼ（EC 3.5.2.3）の決定のための基質であり、カルバモイル-アスパラギン酸-OHをL-5,6-ジヒドロオロチンに環化する触媒作用を持ちます。この酵素はピリミジン核酸生合成経路に存在し、新しい抗腫瘍剤の設計に重要な治療標的です。その活性は分光光度法で測定され、230 nmで吸収増加が測定されました（ε = 1170 M?¹cm?¹、Km = 0.47 mM、kcat = 143 s?¹）。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 13184-27-5
Sample solution is provided at 25 µL, 10mM.
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Substrate for the determination of E.coli dihydroorotase (EC 3.5.2.3.), which catalyzes the cyclization of carbamoyl-Asp-OH into L-5,6-dihydroorotate. This enzyme being in the biosynthetic pathway of pyrimidine nucleotides, is an important therapeutic
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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