Cyclo(-Gly-Tyr(PO₃H₂)-Val-Pro-Met-Leu) |
カタログ番号GA21333 |
PDGF受容体BサブユニットのTyr??¹周辺の自己リン酸化セグメントに対応する環状ヘキサペプチドc(GYVPML)は、有丝分裂原性シグナル伝達経路を仲介する受容体チロシンキナーゼ/ srcホモロジー領域2(SH2)相互作用の阻害剤として機能します。
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Cas No.: 158778-21-3
Sample solution is provided at 25 µL, 10mM.
The cyclic hexapeptide c(GYVPML), corresponding to the autophosphorylation segment around Tyr¹ of the PDGF receptor B subunit, serves as an inhibitor of receptor tyrosine kinase/src homology region 2 (SH2) interactions that mediate mitogenic signa
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