Fmoc-Ala-(Dmb)Gly-OH |
カタログ番号GA21499 |
Dmb基は、偽プロリン残基と同様にFmoc-SPPS中の集合した配列を効率的に崩壊させます。Hmbジペプチドとは異なり、Dmbジペプチドはオキサゼピノンを形成することができないため、スムーズにカップリングされます。TFAクレイベージの最終段階でスカベンジャーが存在する場合、Dmbは除去されます。
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Cas No.: 1188402-17-6
Sample solution is provided at 25 µL, 10mM.
Introduction of the Dmb-moiety disrupts aggregated sequences during Fmoc-SPPS as efficiently as a pseudoproline residue. Dmb dipeptides couple smoothly, as, contrary to Hmb dipeptides, they cannot form oxazepinones. Dmb is removed during the final TFA
Average Rating: 5
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