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Fmoc-Ser(BSi)-OH

カタログ番号GA21793

BSi(またはTBDMS)エーテルは、Ser水酸基のtBuエーテル保護よりもTFAに対してやや不安定です。Ser(TBDMS)は、DMF中でBu?Nフッ化物を用いてBoc / tBuと選択的にクリアされることがありますが、この条件下ではFmocも除去されます。

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Fmoc-Ser(BSi)-OH 化学構造

Cas No.: 146346-81-8

サイズ 価格 在庫数 個数
1g
$272.00
在庫あり
5g
$1,088.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

The BSi (or TBDMS) ether is somewhat more labile towards TFA than the tBu ether protection of the Ser hydroxyl moiety. Ser(TBDMS) can be cleaaved selectiviely in the presence of Boc/tBu with BuN fluoride in DMF, but Fmoc is removed under these conditio

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