H-Glu(EDANS)-Pro-Leu-Phe-Ala-Glu-Arg-Lys(DABCYL)-OH |
カタログ番号GA22349 |
µ-カルパインのための内部消火基質で、切断結合を挟んだ最適なクレアージュモチーフを持っています。このFRET基質は、アミノ酸配列PLFAERに基づくものであり、天然基質α-スペクトリンの切断部位から派生したEVYGMMよりも18倍以上高いターンオーバー率を示しました。
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Cas No.: 1914987-47-5
Sample solution is provided at 25 µL, 10mM.
Internally quenched substrate for calpain-1 (µ-calpain) with optimal cleavage motifs flanking the scissile bond. The enzyme showed a more than 18-fold higher turnover rate for the hydrolysis of this FRET substrate based on the amino acid sequence P
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