MAC-545496 |
| カタログ番号GC39561 |
MAC-545496 は、糖ペプチド耐性関連タンパク質 R (GraR) のナノモル阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 838810-96-1
Sample solution is provided at 25 µL, 10mM.
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MAC-545496 is a nanomolar inhibitor of glycopeptide-resistance-associated protein R (GraR). MAC-545496 displays strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 is an antivirulence agent that reverses β-lactam resistance in Methicillin-resistant strains (MRSA)[1].
[1]. El-Halfawy OM, et al. Discovery of an antivirulence compound that reverses β-lactam resistance in MRSA. Nat Chem Biol. 2019 Nov 25.
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)
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