Dehydro-ZINC39395747 |
| カタログ番号GC60127 |
Dehydro-ZINC39395747 は、ZINC39395747 の誘導体です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 433248-87-4
Sample solution is provided at 25 µL, 10mM.
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Dehydro-ZINC39395747 is a derivative of ZINC39395747. ZINC39395747 is a potent cytochrome b5 reductase 3 (CYB5R3) inhibitor with an IC50 of 9.14 μM and a Kd of 1.11 μM. ZINC39395747 can increase NO bioavailability in vascular cells[1].
[1]. Rahaman MM, et al. Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability. J Biol Chem. 2015 Jul 3;290(27):16861-72.
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