1-Arachidonoyl-d8-rac-glycerol (Synonyms: 1-AG-d8) |
| カタログ番号GC46480 |
多様な生物学的活性を持つ神経ペプチド
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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1-Arachidonoyl-d8-rac-glycerol (1-AG-d8) is intended for use as an internal standard for the quantification of 1-AG by GC- or LC-MS. 1-AG is a weak cannabinoid (CB1) receptor agonist and may have other pharmacologic properties.1 1-AG is an isomer of 2-AG. 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency.
1.Sugiura, T., Kodaka, T., Kondo, S., et al.Is the cannabinoid CB1 receptor a 2-arachidonoylglycerol receptor• Structural requirements for triggering a Ca2+ transient in NG108-15 cellsJ. Biochem.122(4)890-895(1997)
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