JWH 398 N-pentanoic acid metabolite-d5 (Synonyms: JWH 398 N(5carboxypentyl) metabolited5)

JWH 398 N-pentanoic acid metabolite-d₅ contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 398 N-pentanoic acid metabolite by GC- or LC-mass spectrometry. JWH 398 is a synthetic cannabinoid (CB) that acts as an agonist at both the central CB₁ receptor and the peripheral CB₂ receptor (K_is = 2.3 and 2.8 nM, respectively).¹ It has been detected as an additive of herbal mixtures.² JWH 398 N-pentanoic acid metabolite is an expected phase I metabolite of JWH 398. The biological and toxicological properties of this compound have not been characterized. This product is intended for forensic and research purposes.

1.Huffman, J.W.Cannabimimetic indoles, pyrroles, and indenes: Structure-activity relationships and receptor interactionsThe cannabinoid receptors49-95(2009) 2.Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y.Survey of current trends in the abuse of psychotropic substances and plants in JapanLeg. Med. (Tokyo)13(3)109-115(2011)