Taurocholic Acid-d4 (sodium salt) (Synonyms: Ethanesulfonic Acid-d4, TCA-d4) |
| カタログ番号GC48128 |
胆汁酸定量のための内部標準
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2410279-93-3
Sample solution is provided at 25 µL, 10mM.
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Taurocholic acid-d4 (TCA-d4) is intended for use as an internal standard for the quantification of TCA by GC- or LC-MS. TCA is a taurine-conjugated form of the primary bile acid cholic acid .1 Serum levels of TCA are decreased in patients with Crohn's disease and those with ulcerative colitis with no extraintestinal manifestations, but are increased in patients with ulcerative colitis accompanied by hepatobiliary disease.2
1.Lefebvre, P., Cariou, B., Lien, F., et al.Role of bile acids and bile acid receptors in metabolic regulationPhysiol. Rev.89(1)147-191(2009) 2.Gnewuch, C., Liebisch, G., Langmann, T., et al.Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel diseaseWorld J. Gastroenterol.15(25)3134-3141(2009)
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