3-Acetyl Betulin (Synonyms: 3-O-Acetyl Betulin) |
カタログ番号GC48481 |
ベチュリンの誘導体
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Cas No.: 27570-20-3
Sample solution is provided at 25 µL, 10mM.
3-Acetyl betulin is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1,2 It is an intermediate in the synthesis of various lupane and germanicane triterpenes and saponins with anticancer activity.
1.Thibeault, D., Gauthier, C., Legault, J., et al.Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3β-O-monodesmosidic saponins starting from betulinBioorg. Med. Chem.15(18)6144-6157(2007) 2.B?benek, E., Kadela-Tomanek, M., Chrobak, E., et al.Novel triazoles of 3-acetylbetulin and betulone as anticancer agentsMed. Chem. Res.27(9)2051-2061(2018)
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