Mebicar (Synonyms: Mebikar) |
| カタログ番号GC49319 |
テトラメチルグリセロール (テトラメチルグリコールリル) は、抗不安活性を備えた GABA 受容体に作用する低分子です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 10095-06-4
Sample solution is provided at 25 µL, 10mM.
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Mebicar is an anxiolytic with antiepileptic activity.1,2 In vivo, mebicar (10 mg/kg) reduces anxiety-like behavior and decreases stress-induced increases in serum corticosterone and pro-inflammatory cytokine levels in a mouse model of intermittent unpredictable stress.1 It inhibits epileptic activity in a rat model of penicillin-induced focal epilepsy.2
1.Kim, C.Y., Kim, Y.G., Sin, S.J., et al.Preventive effect of mebicar and ginsenoside Rg1 on neurobehavioral and immunological disruptions caused by intermittent unpredictable stress in miceNeuroImmunoModulation25(1)49-58(2018) 2.Rekhtman, M.B., Torshin, V.I., and Darinski?, N.V.Effect of mebikar on focal epileptic activityBiull. Eksp. Biol. Med.91(2)178-181(1981)
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